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段亚琦


教授、硕士生导师、病理系副主任


联系方式:yqduan@mails.tjmu.edu.cn



个人简介

病理学系教授,教育部新世纪人才。从事病理学教学、科研和临床工作。主要研究方向为肿瘤病理及心血管病理。现担任湖北省医学会病理学分会副主任委员、中华医学会病理学分会国际交流工作委员会委员、中华医学会/中国医师协会病理学分会分子病理委员会委员及中华医学会病理学分会骨和软组织肿瘤学组委员。主持国家自然科学基金青年基金、面上基金,国家教委归国留学人员启动基金及武汉市科研基金等。所获科学研究成果以第一或通讯作者发表JCI、CCR等SCI论文三十余篇。


近年代表作

1. Prognostic value and non-neuroendocrine role of INSM1 in small cell lung cancer. Xu X, Wang G, Duan Y*, Huo Z*. Pathol Res Pract. 2022 Jan;229:153693.

2. SOX11 is a sensitive and specific marker for pulmonary high-grade neuroendocrine tumors. Lu Yu, Yuting Dong, Jin Xue, Sanpeng Xu, Guoping Wang, Dong Kuang*, Yaqi Duan*. Diagn Pathol. 2022 Jan 7;17(1):2.

3. Prediction of the World Health Organization Grade of rectal neuroendocrine tumors based on CT histogram analysis. Liang P, Xu C, Tan F, Li S, Chen M, Hu D, Kamel I, Duan Y*, Li Z*. Cancer Med. 2021 Jan;10(2):595-604.

4. Serum semaphorin 4C as a diagnostic biomarker in breast cancer: A multicenter retrospective study. Wang Y#, Qiao L#, Yang J#, Li X#, Duan Y#, Liu J, Chen S, Li H, Liu D, Fang T, Ma J, Li X, Ye F, Wan J, Wei J, Xu Q, Guo E, Jin P, Wu M, Zhang L, Xia Y, Wu Y, Shao J, Feng Y, Zhang Q, Yang Z, Chen G, Zhang Q, Li X, Wang S, Hu J, Wang X, Tan MP, Takabe K, Kong B, Yang Q, Ma D, Gao Q. Cancer Commun (Lond). 2021 Dec;41(12):1373-1386.

5. Rho-kinase inhibition by Fasudil promotes tumor maturation and apoptosis in small-cell lung cancer. Huo Z, Su Y, Dong Y, Zheng Y, Zhang Q, Duan Y#, Wang G*. Am J Transl Res. 2020 Aug 15;12(8):4354-4370.

6. Deficiency of Tfh Cells and Germinal Center in Deceased COVID-19 Patients. Ya-qi Duan, Ming-hui Xia, Liang Ren, Yan-fang Zhang, Qi-lin Ao, San-peng Xu, Dong Kuang, Qian Liu, Bing Yan, Yi-wu Zhou, Qian Chu, Liang Liu, Xiang-Ping Yang, Guo-ping Wang. Current Medical Science volume 40, pages618–624(2020)

7. Pathological changes in the lungs and lymphatic organs of twelve COVID-19 autopsy cases. Qian Liu#, Yu Shi#, Jun Cai#, Yaqi Duan#, Guoping Wang, Liang Liu, Xiu-Wu Bian. et al. National Science Review, Volume 7, Issue 12, December 2020, Pages 1868–1878.

8. Clinicopathological Features and Outcomes of Acute Kidney Injury in Critically Ill COVID-19 with Prolonged Disease Course: A Retrospective Cohort. Xia P#, Wen Y#, Duan Y#, Su H, Cao W, Xiao M, Ma J, Zhou Y, Chen G, Jiang W, Wu H, Hu Y, Xu S, Cai H, Liu Z, Zhou X, Du B, Wang J, Li T, Yan X, Chen L, Liang Z, Zhang S, Zhang C, Qin Y, Wang G, Li X. J Am Soc Nephrol. 2020 Sep;31(9):2205-2221.

9. Rho-kinase inhibition by Fasudil promotes tumor maturation and apoptosis in small-cell lung cancer. Huo Z, Su Y, Dong Y, Zheng Y, Zhang Q, Duan Y*, Wang G*. Am J Transl Res. 2020 Aug 15;12(8):4354-4370.

10. TFEB mediates immune evasion and resistance to mTOR inhibition of renal cell carcinoma via induction of PD-L1. Zhang C#, Duan Y#, Xia M, Dong Y, Chen Y, Zheng L, Chai S, Zhang Q, Wei Z, Liu N, Wang J, Sun C, Tang Z, Cheng X, Wu J, Wang G, Zheng F, Laurence A, Li B, Yang XP. Clin Cancer Res. 2019 Nov 15;25(22):6827-6838

11. SOX11: A Potentially Useful Marker in Surgical Pathology A Systematic Analysis of SOX11 Expression in Epithelial and Nonepithelial Tumors. Xu S, Dong Y, Huo Z, Yu L, Xue J, Wang G*, Duan Y*. Histopathology. 2019 Feb;74(3):391-405.


12. miR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT. Wang Y, Li J, Kuang D, Wang X, Zhu Y, Xu S, Chen Y, Cheng H, Zhao Q, Duan Y*, Wang G*. Cell Commun Signal. 2018 Apr 16;16(1):16.


13. Fleischmann,B.K#., Duan,Y#., Fan,Y., Schoneberg,T., Ehlich,A., Lenka,N., Viatchenko-Karpinski,S., Pott,L., Hescheler,J., and Fakler,B. Differential subunit composition of the G protein-activated inward-rectifier potassium channel during cardiac development. J. Clin. Invest. 2004; 114, 994-1001.






  • 华中科技大学同济医学院病理学系
    华中科技大学同济医学院附属同济医院病理研究所(科) 
    湖北省武汉市航空路13号 邮编:430030